Oral Cancer

Oral cancer starts in the mouth, which is also called the oral cavity. The oral cavity includes the lips, inside lining of the lips and cheeks, teeth, gums, the front of the tongue, the floor of the mouth below the tongue, and the bony roof of the mouth. Oral cancer is the 16th most common cancer worldwide. According to Globocan 2020, there were over 375,000 new diagnoses globally. These cancers are more prevalent in men, where 264,000 men were diagnosed vs. 114,000 women. The incidence of oral cancers vary globally, and Papua New Guinea and Sri Lanka had the highest rates, with the United States ranking #30.1

Oral Cancer

A few risk factors for oral cancer include:2

  • Gender: Oral cancer is twice as common in men than women.
  • Age: Most people diagnosed with oral cancer are over the age of 55.
  • Tobacco Use
  • Alcohol Use
  • Ultraviolet (UV) light: Exposure to sunlight for long periods of time increases the risk of lip cancer.
  • Poor Nutrition
  • Having a Weakened Immune System
  • Weakened Immune System
  • Graft-Versus-Host Disease: This is a condition that sometimes occurs after a stem cell transplant and can cause an increase in risk of oral cancer.
  • Genetic Syndromes: Risk increases for people with certain syndromes caused by inherited gene mutations.
  • Lichen Planus: This disease affects the skin, but can affect the lining of the mouth and throat. A severe case may increase the risk of oral cancer.

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