Hodgkin Lymphoma

Lymphoma is the most common type of blood cancer that begins in the lymphocytes, which are white blood cells that fight infection. The two main types of lymphoma are Hodgkin lymphoma (HL), and non-Hodgkin lymphoma (NHL). HL usually begins in the B lymphocytes, which make proteins called antibodies that help protect the body from germs. There were 82,469 new HL diagnoses worldwide in 2022.1 It’s estimated that 8,720 people in the U.S. will be diagnosed in 2025.2 There are different types of HL, which grow, spread and are treated differently. Classic Hodgkin lymphoma makes up >90% of diagnoses and nodular lymphocyte-predominant Hodgkin lymphoma makes up ~5% of HL diagnoses.3

Hodgkin Lymphoma Cancer

A few risk factors for Hodgkin lymphoma (HL) include4:

  • Age: Although people can be diagnosed at any age, HL is most common in early (20s) and late (>55) adulthood.
  • Family History: Although most people with HL don’t have a family history, the risk increases in young people that have a brother or sister with HL.
  • Epstein-Barr Virus (EBV) Infection/Mononucleosis

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